Hi,
I'm running FS2000 on winxp, works like a charm. On more modern PC's, u might run into a problem with the 16:9 resolution, since in the days of FS2000 a 4:3 resolution was common. If it doesn't run at all in w10, u can try a Win98 Emulation, many youtube Videos of fs98 and fs2000 are using it.
Hope this helps,
SAS857