Thanks for your reply!
When pressed in flight. For instance, flying a Baron 58, the mag/starter knob on the panel works fine. The landing gear works fine as well. The rest do not respond. The switch panels do not show up in Options in FSX, never did. When you download the drivers for the panel on Saitek's site, the drivers include an .exe called "SaiPanels" which loads when FSX starts. This basically assigns all of the switches/knob/lever to the defaults. If your craft has retractable gear, then the lever works, however if you are flying a Cessna 152/172, the gear lever is disabled.
I've attached an image which shows everything that does not work. It worked great in Windows 7 and even in Windows 10 prior to me wiping my computer and installing a fresh install of Windows 10 and FSX. Now, everything inside the red area just doesn't respond within FSX.