My guess is that the GoFlight module is not being initialized when FSX starts. I have had no problem. Check the following:
1. GFDev.dll and GFDevFSX.exe need to be in the FSX\Modules directory.
2. Since you are running FSUIPC4 do you have an FSUIPC.ini file? That is also in the FSX\Modules directory. My file contains the following 2 lines:
where D: is the drive where your FSX resides.
Also, I found that the GF-MCP module does not like to be attaced through a USB hub, even a powered one. I have the MCP plugged into a USB on the computer. My other modules are connected through powered USB hubs.
i7 975 @ 4.0,NH-D14, ASUS P6T Deluxe V2, Win 7 64bit, 6GB, GTX570, WD 1TB, WD 300 GB VRAP, WD 2TB, Antec 1200 tower,FSX Gold, FSUIPC, UTX, GEX, Simplugins